Process of making abaloparatide
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United States of America Patent
Stats
-
Nov 7, 2023
Grant Date -
N/A
app pub date -
May 19, 2023
filing date -
May 20, 2022
priority date (Note) -
In Force
status (Latency Note)
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Abstract
Disclosed herein is an improved process for preparing abaloparatide. The process generally utilizes solid phase peptide synthesis employing an Fmoc-protection scheme. Incorporating a systematic recoupling step of a glutamine residue (Gln16) has been found to minimize the formation of an undesirable des-Gln16 abaloparatide impurity, which is often obtained in significant quantities in the conventional process.
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International Classification(s)
- 2023 Application Filing Year
- A61K Class
- 11803 Applications Filed
- 2060 Patents Issued To-Date
- 17.46 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- A61K Class
- 0 % this patent is cited more than
- 2 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 3.5 Year Payment | $1600.00 | $800.00 | $400.00 | May 7, 2027 |
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | May 7, 2031 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | May 7, 2035 |