Enzyme for synthesizing hydroxyl acetaldehyde and/or 1,3-dihydroxyacetone by catalyzing formaldehyde, and applications thereof

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United States of America Patent

PATENT NO 11802280
SERIAL NO

16483716

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Abstract

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An enzyme synthesizes hydroxyl acetaldehyde and/or 1,3-dihydroxyacetone by catalyzing formaldehyde. Site-directed mutation of benzoylformate decarboxylase (BFD) creates a mutant of the enzyme, which can polymerize the formaldehyde, A phosphoketalose (F/XPK) generates acetyl phosphoric acid from the hydroxyl acetaldehyde or 1,3-dihydroxyacetone (DHA). Combination with phosphotransacetylase (Pta) provides a route from the formaldehyde to acetyl coenzyme A in three steps.

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Patent Owner(s)

Patent OwnerAddress
TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY CHINESE ACADEMY OF SCIENCES300450 NO 32 XIQI ROAD AIRPORT ECONOMIC ZONE BINHAI NEW AREA TIANJIN TIANJINCITY TIANJINCITY 300450

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gou, Junran Tianjin, CN 1 0
Jiang, Huifeng Tianjin, CN 4 9
Liu, Yuwan Tianjin, CN 1 0
Lu, Lina Tianjin, CN 11 54
Lu, Xiaoyun Tianjin, CN 12 25
Yang, Sheng Tianjin, CN 131 844
Yang, Yiqun Tianjin, CN 9 21

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