Manipulation of beads in droplets and methods for manipulating droplets

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United States of America Patent

PATENT NO 11789015
APP PUB NO 20200393452A1
SERIAL NO

16948074

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Abstract

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Provided herein are methods of splitting droplets containing magnetically responsive beads in a droplet actuator. A droplet actuator having a plurality of droplet operations electrodes configured to transport the droplet, and a magnetic field present at the droplet operations electrodes, is provided. The magnetically responsive beads in the droplet are immobilized using the magnetic field and the plurality of droplet operations electrodes are used to split the droplet into first and second droplets while the magnetically responsive beads remain substantially immobilized.

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Patent Owner(s)

Patent OwnerAddress
ADVANCED LIQUID LOGIC INC5200 ILLUMINA WAY SAN DIEGO CA 92122

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eckhardt, Allen E Durham, US 69 4151
Pamula, Vamsee K Cary, US 132 12386
Pollack, Michael G Durham, US 139 12816
Sista, Ramakrishna Cary, US 45 1544
Srinivasan, Vijay Cary, US 197 9915

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