Immunological targeting of pathological tau proteins

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United States of America Patent

PATENT NO 11787854
APP PUB NO 20210061894A1
SERIAL NO

17090359

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Abstract

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The present invention relates to methods and compositions for treating, preventing, and diagnosing Alzheimer's Disease or other tauopathies in a subject by administering an immunogenic tau peptide or an antibody recognizing the immunogenic tau epitope under conditions effective to treat, prevent, or diagnose Alzheimer's Disease or other tauopathies. Also disclosed are methods of promoting clearance of aggregates from the brain of the subject and of slowing progression of tau-pathology related behavioral phenotype in a subject.

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Patent Owner(s)

Patent OwnerAddress
NEW YORK UNIVERSITY70 WASHINGTON SQUARE SOUTH NEW YORK NY 10012

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sigurdsson, Einar M Scarsdale, US 26 462

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