Composition of subunit dengue vaccine

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United States of America Patent

PATENT NO 11786587
APP PUB NO 20200397884A1
SERIAL NO

16906134

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Abstract

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The present invention relates to a composition of subunit dengue vaccine comprising a fusion protein of conjugating or connecting delta C nonstructural protein 1 (NS1ΔC or truncated NS1ΔC) to at least one polypeptides of NS3c (or truncated NS3c) and/or consensus envelope protein domain III (cEDIII), thereby enhancing better protection against DENV challenge and alleviating associated pathological effects.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL CHENG KUNG UNIVERSITYNO 1 UNIVERSITY ROAD TAINAN 701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Hsin-Wei Miaoli County, TW 37 141
Chuang, Yung-Chun Tainan, TW 21 31
Ho, Tzong-Shiann Tainan, TW 5 2
Lin, Yee-Shin Tainan, TW 7 6
Shieh, Dar-Bin Tainan, TW 41 139
Wan, Shu-Wen Kaohsiung, TW 1 1
Wang, Shu-Ying Tainan, TW 1 1
Yeh, Trai-Ming Tainan, TW 4 1
Yu, Chia-Yi Tainan, TW 1 1

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