Arteriosclerosis and cancer detection method using deoxyhypusine synthase gene as indicator

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11782061
APP PUB NO 20170343547A1
SERIAL NO

15524899

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present inventors have surprisingly found that a deoxyhypusine synthase (DHPS) gene, which was previously reported to correlate with prostate cancer and cervical cancer, is highly responsive to arteriosclerosis or digestive system cancer, whereby the gene can be used as a desired marker for arteriosclerosis or digestive system cancer. The present invention has been accomplished on the basis of this finding. Specifically, the present invention provides a method for determining arteriosclerosis or digestive system cancer, which method includes detecting expression of a deoxyhypusine synthase gene in a test sample (preferably a blood sample), and determining arteriosclerosis or digestive system cancer of a test subject from which the test sample has been obtained, on the basis of an increase in the gene expression as an index.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
FUJIKURA KASEI CO LTDTOKYO 174-0046
NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITYCHIBA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hiwasa, Takaki Chiba, JP 12 8
Kuroda, Hideyuki Kuki, JP 11 80
Nakamura, Rika Kuki, JP 7 3
Saeki, Naokatsu Chiba, JP 5 3
Takiguchi, Masaki Chiba, JP 8 12
Tomiyoshi, Go Kuki, JP 7 3

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 Apr 10, 2027
7.5 Year Payment $3600.00 $1800.00 $900.00 Apr 10, 2031
11.5 Year Payment $7400.00 $3700.00 $1850.00 Apr 10, 2035
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00