Methods of use of ultra-high dose rate radiation and therapeutic agent

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United States of America Patent

PATENT NO 11771920
SERIAL NO

17486169

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Abstract

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Methods for treating tumors by administering FLASH radiation and a therapeutic agent to a patient with cancer are disclosed. The methods provide the dual benefits of anti-tumor efficacy plus normal tissue protection when combining therapeutic agents with FLASH radiation to treat cancer patients. The methods described herein also allow for the classification of patients into groups for receiving optimized radiation treatment in combination with a therapeutic agent based on patient-specific biomarker signatures. Also provided are radiation treatment planning methods and systems incorporating FLASH radiation and therapeutic agents.

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Patent Owner(s)

  • VARIAN MEDICAL SYSTEMS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abel, Eric San Jose, US 42 1464
Girdhani, Swati Fremont, US 3 24
Khuntia, Deepak Los Altos, US 16 128
Kupelian, Patrick Los Angeles, US 6 46
Mansfield, Stanley Oakland, US 35 1650
Parry, Renate Oakland, US 24 158

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