Optically controlled virus protein, gene thereof, and virus vector containing said gene
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United States of America Patent
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Sep 12, 2023
Grant Date -
Mar 25, 2021
app pub date -
Jul 11, 2018
filing date -
Jul 11, 2017
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Abstract
The purpose of the present invention is to develop a virus vector, the activity of which is rendered controllable. A virus protein gene derived from an RNA virus is provided in which a gene encoding an optical switch protein is inserted into a foreign gene introducible region of the virus protein so as to enable expression of the gene. By means of this virus vector, it is possible to control, with irradiation of light, enzyme activity of the virus protein and virus vector activity based thereon.
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