DNA-guided gene editing and regulation

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United States of America Patent

PATENT NO 11746349
APP PUB NO 20210189388A1
SERIAL NO

16076022

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Abstract

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Methods and compositions of altering a eukaryotic cell are described including providing to the eukaryotic cell a guide DNA sequence complementary to a target nucleic acid sequence, providing to the eukaryotic cell an Ago enzyme or a nuclease null Ago protein that interacts with the guide DNA sequence for DNA-guided gene editing and regulation of the target nucleic acid sequence in a site specific manner.

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Patent Owner(s)

Patent OwnerAddress
PRESIDENT AND FELLOWS OF HARVARD COLLEGE17 QUINCY STREET CAMBRIDGE MA 02138

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Church, George M Brookline, US 289 12754
Huang, Po-Yi Boston, US 6 23
Monroe, Margo R Boston, US 3 11
Yang, Luhan Somerville, US 40 2636

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