Deep ultraviolet-excitable water-solvated polymeric dyes

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United States of America Patent

PATENT NO 11732138
APP PUB NO 20230235177A1
SERIAL NO

17955087

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Abstract

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Water solvated polymeric dyes having a deep ultraviolet excitation spectrum are provided. The subject polymeric dyes include a light harvesting multichromophore having conjugation-modifying repeat units incorporated into the polymer backbone to provide segments of π-conjugated co-monomers having limited π-conjugation between segments. Polymeric tandem dyes are also provided that further include a signaling chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. Also provided are labelled specific binding members that include the subject water solvated polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.

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Patent Owner(s)

Patent OwnerAddress
BECTON DICKINSON AND COMPANY1 BECTON DRIVE FRANKLIN LAKES NJ 07417

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bartholomew, Glenn P Escondido, US 49 890
Hollinger, Jonathan Poway, US 4 5
Liang, Yongchao Irvine, US 60 690
Moureau, David San Diego, US 11 22
Wall, Brian Poway, US 21 311
Zhao, Lucy San Diego, US 15 144

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