Hydrophilic berberine-type derivative and application thereof in preparing drug

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United States of America Patent

PATENT NO 11725006
APP PUB NO 20210147409A1
SERIAL NO

17046927

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Abstract

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An 8-dihalomethyl berberine-type quaternary ammonium salt compound represented by general formula (I) or (II) and an application thereof in preparing a drug. The compound shows hydrophilicity and has antimicrobial, anti-inflammatory, anti-ulcerative colitis, and antitumor activities, while having no or low toxicity.

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Patent Owner(s)

Patent OwnerAddress
INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCESNO 1 XIAN NONG TAN STREET XICHENG DISTRICT BEIJING 100050 100050

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deng, Anjun Beijing, CN 4 0
Li, Xiang Beijing, CN 1551 27876
Li, Zhihong Beijing, CN 90 849
Qin, Hailin Beijing, CN 4 0
Song, Huachen Beijing, CN 1 0
Song, Li Beijing, CN 71 895
Tang, Xiaonan Beijing, CN 1 0
Wu, Lianqiu Beijing, CN 4 1
Zhang, Haijing Beijing, CN 5 1
Zhang, Zhihui Beijing, CN 132 1158

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