Bioactive borate glasses
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United States of America Patent
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Aug 15, 2023
Grant Date -
Jun 25, 2020
app pub date -
Mar 4, 2020
filing date -
Nov 20, 2018
priority date (Note) -
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Abstract
An antibacterial composition, includes: a borate-based glass material having a composition of: 0-25 wt. % SiO2, 30-75 wt. % B2O3, 0-10 wt. % P2O5, 0-30 wt. % Al2O3, 0-5 wt. % Li2O, 1-25 wt. % Na2O, 0-15 wt. % K2O, 0-10 wt. % MgO, 10-25 wt. % CaO, 12-30 wt. % MO, 8-25 wt. % R2O, and 30-75 (B2O3+Al2O3), such that at least one of P2O5 or Al2O3 is present, MO is the sum of MgO, CaO, SrO, and BaO, R2O is the sum of Na2O, K2O, Li2O, and Rb2O, and the borate-based glass material is configured to achieve at least a 3.5-log kill rate of at least one of E. coli, P. gingivalis, or S. mutans bacteria.
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