Lipoprotein analysis by differential charged-particle mobility

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United States of America Patent

PATENT NO 11680949
APP PUB NO 20210181217A1
SERIAL NO

17188855

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Abstract

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The invention provides methods of preparation of lipoproteins from a biological sample, including HDL, LDL, Lp(a), IDL, and VLDL, for diagnostic purposes utilizing differential charged particle mobility analysis methods. Further provided are methods for analyzing the size distribution of lipoproteins by differential charged particle mobility, which lipoproteins are prepared by methods of the invention. Further provided are methods for assessing lipid-related health risk, cardiovascular condition, risk of cardiovascular disease, and responsiveness to a therapeutic intervention, which methods utilize lipoprotein size distributions determined by methods of the invention.

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Patent Owner(s)

Patent OwnerAddress
QUEST DIAGNOSTICS INVESTMENTS INCORPORATEDWILMINGTON DE 19899

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benner, W Henry Danville, US 25 278
Blanche, Patricia J Berkeley, US 14 127
Caulfield, Michael P San Clemente, US 31 224
Cornell, Earl Antioch, US 11 308
Krauss, Ronald Berkeley, US 15 42
Lee, Gloria Kwangja Ladera Ranch, US 16 125
Li, Shuguang Rancho Santa Margarita, US 34 185
Reitz, Richard E San Clemente, US 97 1106

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