Crystalline forms of ozanimod and ozanimod hydrochloride, and processes for preparation thereof

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United States of America Patent

PATENT NO 11680050
APP PUB NO 20200157065A1
SERIAL NO

16748303

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Abstract

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The present disclosure is directed to novel crystalline forms of ozanimod and ozanimod hydrochloride, as well as preparation method thereof. Said crystalline forms of ozanimod and ozanimod hydrochloride can be used for treating autoimmune diseases, particularly used for preparing drugs for treating multiple sclerosis and ulcerative colitis. The crystalline forms of the present disclosure have one or more advantages in solubility, melting point, stability, dissolution, bioavailability and processability and provide new and better choices for the preparation of ozanimod drug product, and are very valuable for drug development.

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Patent Owner(s)

  • RECEPTOS LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Minhua Suzhou, CN 84 96
Yan, Kaiqiang Suzhou, CN 10 20
Yang, Chaohui Suzhou, CN 28 97
Zhai, Xiaoting Suzhou, CN 12 23
Zhang, Xiaoyu Suzhou, CN 147 948
Zhang, Yanfeng Suzhou, CN 177 515

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