Production and use of phosphoethanolamine cellulose and derivatives
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United States of America Patent
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Jun 6, 2023
Grant Date -
Aug 26, 2021
app pub date -
May 5, 2021
filing date -
Aug 18, 2016
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Abstract
Phosphoethanolamine cellulose and methods of making and using it are disclosed. In particular, the invention relates to a method of producing a phosphoethanolamine cellulose biosynthetically using a BcsG phosphoethanolamine transferase for cellulose modification. Recombinant constructs encoding BcsG are described, including constructs encoding BcsG by itself or in combination with BcsE and BcsF, which increase the extent of cellulose modification and the amount of modified cellulose produced. Production of phosphoethanolamine cellulose in cell culture and derivatization of phosphoethanolamine cellulose are also described.
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