Linkers for antibody drug conjugates

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11629122
APP PUB NO 20200115326A1
SERIAL NO

16616148

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Abstract

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In one aspect, the present disclosure provides compounds of the formula (I): wherein the variables are as defined herein. In another aspect, the present disclosure provides compounds of the formula (V): wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure provides antibody drug conjugates comprising compounds of the present disclosure. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds and anti-body drug conjugates disclosed herein.

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Patent Owner(s)

Patent OwnerAddress
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM210 WEST 7TH STREET AUSTIN TX 78701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
An, Zhiqiang Houston, US 59 231
Anami, Yasuaki Houston, US 3 7
Tsuchikama, Chisato Houston, US 3 7
Tsuchikama, Kyoji Houston, US 3 7
Zhang, Ningyang Houston, US 4 7

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