Method for the diagnosis, prognosis and treatment of cancer metastasis

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United States of America Patent

PATENT NO 11591599
APP PUB NO 20190309299A1
SERIAL NO

15944499

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Abstract

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This study describes a method to determine the likelihood of the development of metastasis in a subject suffering from cancer, in addition to a method to design a customized therapy in a subject suffering from cancer, in particular breast, colon, lung, kidney and thyroid cancer, based on the determination of the expression level of one or more genes whose expression is modulated by an increase in c-MAF expression. It also describes a method for the identification of marker genes with a propensity for metastatic cancer based on inducing the modulation of the c-MAF expression Finally, the use of PTHLH and PODXL inhibitors and RERG activators in the treatment and/or prevention of the cancer, in particular breast, colon, lung, kidney and thyroid cancer.

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Patent Owner(s)

  • FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA); INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇAIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arnal, Anna Barcelona, ES 15 234
Gomis, Roger Barcelona, ES 30 457
Pavlovic, Milica Lajkovac, RS 15 234
Planet, Evarist Barcelona, ES 14 228
Tarragona, Maria Barcelona, ES 15 234

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