Drug-loaded biodegradable microbead compositions including drug-containing vesicular agents

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United States of America Patent

PATENT NO 11590080
APP PUB NO 20210052499A1
SERIAL NO

16913314

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Abstract

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Drug-loaded microbead compositions include microbeads of a biodegradable material and vesicular agents located within or associated with the biodegradable material of the microbeads. The vesicular agents include a lipid bilayer and comprise liposomes or ethosomes. The drug-loaded microbeads include a first therapeutic agent associated with the vesicular agents, and a second therapeutic agent different from the first therapeutic agent. The vesicular agents include a lipid bilayer surrounding a vesicular core. The second therapeutic agent is contained within the microbeads or associated with the microbeads through ionic or non-covalent interaction and may or may not be associated with the vesicular agents. Drug-loaded biodegradable microbead compositions include microbeads of biodegradable material and a therapeutic agent.

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Patent Owner(s)

Patent OwnerAddress
C R BARD INC730 CENTRAL AVENUE MURRAY HILL NJ 07974

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Afonina, Elena Franklin Lakes, US 6 64
Do, Hiep Franklin Lakes, US 20 1377
Goel, Emily Franklin Lakes, US 5 2
Guryev, Oleg Franklin Lakes, US 13 5
Lecy, Cyal Franklin Lakes, US 7 3
Mehrpouyan, Majid Franklin Lakes, US 16 167
Randall, Michael Franklin Lakes, US 29 693
Sharkey, Marybeth Franklin Lakes, US 15 16
Wang, Jeffrey Franklin Lakes, US 62 1636

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