Polyethylene glycol-conjugated glucocorticoid prodrugs and compositions and methods thereof

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United States of America Patent

PATENT NO 11583541
APP PUB NO 20210252018A1
SERIAL NO

17188309

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Abstract

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Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.

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Patent Owner(s)

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BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA3835 HOLDREGE STREET LINCOLN NE 68583

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jia, Zhenshan Omaha, US 7 12
Wang, Dong Omaha, US 600 4166
Wang, Xiaobei Omaha, US 8 12
Yuan, Fang Wheaton, US 420 886

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