Chloroquine gel and preparation method and application thereof

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United States of America Patent

PATENT NO 11564891
SERIAL NO

17472541

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Abstract

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A product for preventing and treating external genitalia infection and/or flat warts is provided, wherein the product comprises a chloroquine nanosphere. The chloroquine nanosphere comprises a water-soluble nanosphere carrier, and chloroquine or a chloroquine derivative. A mass ratio of the chloroquine or the chloroquine derivative to the water-soluble nanosphere carrier during preparation ranges from 1:3 to 1:5. A loading rate of the chloroquine or the chloroquine derivative in the prepared chloroquine nanosphere ranges from 3.0% to 21.6%. The water-soluble nanosphere carrier is water-soluble chitosan; a deacetylation degree of the water-soluble chitosan ranges from 80% to 95%, and a viscosity-average molecular weight thereof ranges from 3000 to 5000 g/mol. The chloroquine derivative is selected from one or more of hydroxychloroquine, chloroquine phosphate or chloroquine sulfate.

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Patent Owner(s)

Patent OwnerAddress
GUANGZHOU HYBRIBIO MEDICINE TECHNOLOGY LTD510700 4TH FLOOR NO 2 REAGENT WORKSHOP 71 FENGHUANG SANHENG ROAD ZHONGXIN KNOWLEDGE CITY JIULONG TOWN HUANGPU DISTRICT GUANGZHOU CITY GUANGDONG PROVINCE GUANGZHOU CITY GUANGDONG PROVINCE 510700

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Li, Xiangling Guangdong, CN 5 9
Wang, Jianyu Guangdong, CN 31 146
Wang, Ting Guangdong, CN 763 6307
Xie, Longxu Guangdong, CN 4 0
Yuan, Manli Guangdong, CN 4 3

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