Processes for the preparation of SGLT-2 inhibitors, intermediates thereof
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United States of America Patent
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Jan 10, 2023
Grant Date -
Oct 22, 2020
app pub date -
May 18, 2020
filing date -
May 30, 2017
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Abstract
The present invention relates to modified, improved processes for the preparation of sodium glucose co-transporter 2 (SGLT-2) inhibitors and intermediates thereof. More particularly, the present invention relates to improved processes for the preparation of gliflozin compounds such as empagliflozin and dapagliflozin, intermediates thereof. The product obtained from the processes of present invention may be amorphous or crystalline. Also, the products obtained from the present invention may be used for the preparation of medicaments for the prevention and/or treatment of diseases and conditions associated with SGLT-2 inhibition.
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