Cyclic amidine compounds for the treatment of autoimmune disease

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United States of America Patent

PATENT NO 11548884
APP PUB NO 20210340134A1
SERIAL NO

17274040

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Abstract

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The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds as antagonist of TLR7 and/or TLR8 and/or TLR9 in the treatment of autoimmune diseases as well as auto-inflammation diseases.

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Patent Owner(s)

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HOFFMANN-LA ROCHE INC150 CLOVE ROAD OVERLOOK AT GREAT NOTCH SUITE 8 LITTLE FALLS NJ 07424

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dey, Fabian Basel, CH 50 126
Qiu, Zongxing Shanghai, CN 13 208
Shen, Hong Shanghai, CN 243 3651
Xu, Hongtao Shanghai, CN 44 491
Zhu, Wei Shanghai, CN 383 5693
Zou, Ge Shanghai, CN 19 112

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