Methods of treating disorders associated with castor

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United States of America Patent

PATENT NO 11547709
APP PUB NO 20210023081A1
SERIAL NO

16957996

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Abstract

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The present disclosure relates to methods of treating a coenzyme A reduction, elevation, sequestration, toxicity, or redistribution (CASTOR) disease such as, for example, defects in fatty acid oxidation enzymes, methylmalonic acidemia, glutaric acidemia, propionic academia, and HMG-CoA lyase, via small molecule modulators of CoA levels. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

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Patent Owner(s)

Patent OwnerAddress
ST JUDE CHILDREN'S RESEARCH HOSPITAL INC262 DANNY THOMAS PLACE MAIL STOP 742 MEMPHIS TN 38105-3678

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Edwards, Anne V Memphis, US 17 23
Jackowski, Suzanne Bartlett, US 9 6
Lee, Richard E Cordova, US 30 241
Liu, Jiuyu Collierville, US 10 11
Reddy, T Jagadeeswar Pierrefonds, CA 11 56
Rock, Charles O Bartlett, US 12 37
Sharma, Lalit Kumar South San Francisco, US 6 5
Subramanian, Chitra Cordova, US 41 325
Tangallapally, Rajendra P Collierville, US 5 2
Yun, Mi Kyung Collierville, US 13 22
Zamboni, Robert Beaconsfield, CA 53 319

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