neutral protease

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United States of America Patent

PATENT NO 11542489
APP PUB NO 20210355472A1
SERIAL NO

17386106

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Abstract

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The present disclosure provides the sequence of a Paenibacillus polymyxa preproenzyme which is the precursor of a neutral protease, expression thereof in a transformed host organism, and methods for production of the neutral protease, by recombinant means. Further, use of the recombinantly produced neutral protease is disclosed in the field of cell biology, particularly for the purpose of tissue dissociation. The disclosure also includes blends with other proteases. Further disclosed are nucleotide sequences encoding the neutral protease.

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Patent Owner(s)

Patent OwnerAddress
ROCHE DIAGNOSTICS OPERATIONS INC9115 HAGUE ROAD INDIANAPOLIS IN 46250-0457

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Greiner-Stoeffele, Thomas Soemmerda, DE 15 53
Schoenert, Stefan Leipzig, DE 9 15

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