Protein translation inhibitors and uses thereof
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United States of America Patent
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Nov 29, 2022
Grant Date -
Nov 26, 2020
app pub date -
May 20, 2020
filing date -
May 23, 2019
priority date (Note) -
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Abstract
Provided herein are protein translation inhibitors and pharmaceutical compositions thereof that bind to an RNA Recognition motif in heterogeneous ribonucleoprotein A18 to inhibit binding to mRNA transcripts thereby inhibiting protein synthesis. Also provided is a method for treating a cancer by administering a pharmaceutically acceptable amounts of at least one of the protein translation inhibitors.
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