Antibodies directed to the deletion mutants of epidermal growth factor receptor and uses thereof

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United States of America Patent

PATENT NO 11492411
SERIAL NO

16673234

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Abstract

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The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.

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Patent Owner(s)

  • AMGEN FREMONT INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Corvalan, Jose R F Foster City, US 3 40
Feng, Xiao Elk Grove, US 62 1106
Foltz, Ian Burnaby, CA 70 1068
Foord, Orit Foster City, US 95 1360
Green, Larry L San Francisco, US 51 1353
Gudas, Jean M Los Angeles, US 12 335
Jia, Xiao-Chi Los Angeles, US 78 1901
Kang, Jaspal Singh Surrey, CA 39 697
Keyt, Bruce A Hillsborough, US 32 582
King, Chadwick Terence North Vancouver, CA 53 1703
Klakamp, Scott L Fremont, US 13 572
Liu, Ying Palo Alto, US 647 4068
Rathanaswami, Palaniswami Vancouver, CA 18 515
Raya, Robert Fremont, US 9 272
Su, Qiaojuan Jane San Jose, US 21 860
Weber, Richard F San Francisco, US 4 12
Yang, Xiao Dong Palo Alto, US 16 334

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