Anti-alpha-v integrin antibody for the treatment of fibrosis and/or fibrotic disorders

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11485786
SERIAL NO

16541650

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The invention relates to the prophylaxis and/or treatment of fibrosis and/or fibrotic diseases by means of antibodies. Above all, the invention relates to the administration of an anti-alpha-v integrin (receptor) antibody to patients suffering from fibrosis and/or fibrotic diseases, including but not limited to systemic sclerosis (SSc). More specifically, the instant invention relates to the treatment of fibrotic diseases of the skin, lung, heart, liver and/or kidney by means of said antibody. Even more specifically, the instant invention relates to the administration of a recombinant, de-immunized monoclonal antibody targeting αv-integrins patients suffering from systemic sclerosis, including, but not limited to systemic sclerosis of the skin, lung, heart and/or kidney by means of the anti-alpha-v integrin antibody DI17E6 and structural mutants or modifications thereof.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
MERCK KGAAFRANKFURTER STRASSE 250 DARMSTADT 64293

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bender, Andrew Reading, US 5 2
Celik, Ilhan Zwingenberg, DE 9 5
Higginbotham, Georgianna Tewksbury, US 2 2
Raab, Sabine Rosbach, DE 5 7
Samy, Eileen Arlington, US 4 16
Staub, Eike Darmstadt, DE 10 8
Urban, Miriam Leidersbach, DE 3 2
Wu, Yin Andover, US 19 95
Xu, Daigen Westford, US 10 156

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 May 1, 2026
7.5 Year Payment $3600.00 $1800.00 $900.00 May 1, 2030
11.5 Year Payment $7400.00 $3700.00 $1850.00 May 1, 2034
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00