Chelator-functionalized glycosaminoglycans
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United States of America Patent
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Oct 25, 2022
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N/A
app pub date -
Aug 27, 2019
filing date -
Aug 27, 2018
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Abstract
A compound includes a polysaccharide moiety and one or more chelating agents. The one or more chelating agents are covalently bonded to the polysaccharide moiety. The polysaccharide moiety can include a glycosaminoglycan moiety, such as a hyaluronic acid polymer or a sulfated glycosaminoglycan moiety. The compound can be used to treat or prevent a disease or disorder in a patient with a metal implant. The compound reduces a concentration of metal particulates or metal ions in the subject.
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