Imaging mass spectrometry system and analytical method using imaging mass spectrometry

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United States of America Patent

PATENT NO 11469087
SERIAL NO

17113544

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Abstract

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Imaging mass spectrometry section (100) performs a mass spectrometric analysis at each of the micro areas set within a measurement area on a target sample, and acquires a graphical image showing a signal-intensity distribution at a specific mass-to-charge ratio or mass-to-charge-ratio range. Quantitative analysis section (300) determines a quantitative value using an analysis result obtained by performing an analysis on the sample collected from each predetermined site within the measurement area of the target sample, using a predetermined analytical technique exhibiting a higher level of quantitative determination performance than the mass spectrometric analysis. Processing section (400) determines the relationship between signal intensity and quantitative value, based on quantitative values determined for the sample at predetermined sites and signal intensities at positions corresponding to the predetermined sites in the signal-intensity distribution, and estimates the quantitative value at an arbitrary position within the signal-intensity distribution, using the relationship.

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Patent Owner(s)

Patent OwnerAddress
SHIMADZU CORPORATIONKYOTO 604-8511

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Yamaguchi, Shinichi Kyoto, JP 185 1147
Yamamoto, Takushi Kyoto, JP 18 836

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