Use of a polypeptide for effecting immune signalling and/or affecting intestinal barrier function and/or modulating metabolic status

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United States of America Patent

PATENT NO 11466057
APP PUB NO 20210147489A1
SERIAL NO

16916459

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Abstract

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It has been found that an extracellular polypeptide derived from Akkermansia municiphila is capable of modulating and/or promoting gut mucosal immune system function and/or maintaining and/or restoring metabolic status and/or increasing the physical integrity of the gut mucosal barrier in a mammal. The polypeptide or host cells comprising such polypeptide may be employed to prevent and/or treat a variety of conditions that benefit from an increased physical integrity of the gut mucosal barrier and/or an improved gut mucosal immune system function and metabolic status.

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Patent Owner(s)

  • WAGENINGEN UNIVERSITEIT; UNIVERSITÉ CATHOLIQUE DE LOUVAIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Belzer, Clara Wageningen, NL 15 58
Cani, Patrice Daniel Brussels, BE 2 3
De, Vos Willem Meindert Ede, NL 38 193

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