Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making
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United States of America Patent
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Oct 4, 2022
Grant Date -
Nov 19, 2020
app pub date -
Aug 3, 2020
filing date -
Sep 7, 2016
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Abstract
Described herein are crystalline forms of pharmaceutically acceptable salts of the lysyl oxidase-like 2 (LOXL2) inhibitor (3-(4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yloxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone. Also described are methods of making the LOXL2 inhibitor, pharmaceutical compositions and medicaments comprising the LOXL2 inhibitor, and methods of using the LOXL2 inhibitor in the treatment of conditions, diseases, or disorders associated with LOXL2 activity.
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