Thermoresponsive cell culture supports
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United States of America Patent
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Aug 16, 2022
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N/A
app pub date -
Jan 4, 2019
filing date -
May 26, 2016
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Abstract
The present invention relates to a cell culture support comprising a substrate and a polymeric blend layer bound to the substrate. The polymeric blend layer comprises at least one thermoresponsive polymer and at least one coupling agent. The coupling agent is a non-protein coupling agent that has functional thiol, ester, epoxy, or aldehyde groups. The cell culture support further includes cells supported by the polymeric blend layer, wherein the thermoresponsive polymer provides for temperature induced detachment of the cells and/or cell sheets.
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