Dielectric sensing to characterize hemostatic dysfunction
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United States of America Patent
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Aug 9, 2022
Grant Date -
Oct 8, 2020
app pub date -
Apr 1, 2020
filing date -
Apr 2, 2019
priority date (Note) -
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Abstract
As one example, an apparatus includes a dielectric microsensor comprising a microfluidic chamber that includes a capacitive sensing structure, the microfluidic chamber including a fluid input port to receive a volume of a blood sample. A bioactive agent is disposed within the chamber to interact with the volume of the blood sample received in the microfluidic chamber. A transmitter provides an input radio frequency (RF) signal to an RF input of the dielectric microsensor. A receiver receives an output RF signal from an RF output of the dielectric microsensor. A computing device that computes dielectric permittivity values of the sample that vary over a time interval based on the output RF signal, the computing device to provide an assessment of hemostatic dysfunction and associated coagulopathy based on the dielectric permittivity values.
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