Bacillus based delivery system and methods of use

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United States of America Patent

PATENT NO 11401498
APP PUB NO 20180250377A1
SERIAL NO

15965034

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Abstract

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Herein a Bacillus exosporium antigen delivery (BEAD) system that provides a means to introduce recombinant proteins or small molecules into the exosporium of members of the B. cereus family of bacteria, i.e. B. anthracis, B. cereus, and B. thuringiensis, is disclosed. The system results in the surface display of recombinant proteins or small molecules such that they can stimulate an immune response. In addition, methods of making and using the system are described.

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Patent Owner(s)

Patent OwnerAddress
THE CURATORS OF THE UNIVERSITY OF MISSOURI316 UNIVERSITY HALL COLUMBIA MO 65211

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Stewart, George C Columbia, US 9 192
Thompson, Brian Matthew Creve Coeur, US 5 178

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