Synthetically functionalized living cells for targeted drug delivery

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11400114
APP PUB NO 20170266317A1
SERIAL NO

15458925

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells can cross the blood-brain barrier while remaining viable after attachment of the functional patch. Functional payloads carried by the patch can include a drug. The patch can include one or more polyelectrolyte multilayers (PEMs).

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Patent Owner(s)

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MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Batrakova, Elena V Chapel Hill, US 8 98
Cohen, Robert E Jamaica Plain, US 49 981
Haney, Matthew J Chapel Hill, US 6 29
Klyachko, Natalia L Moscow, RU 1 0
Polak, Roberta Boston, US 2 1
Rubner, Michael F Westford, US 34 854
Zhao, Yuling Chapel Hill, US 2 3

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