Residence structures and related methods

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11389399
APP PUB NO 20210128460A1
SERIAL NO

17126835

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Certain embodiments comprise administering a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. In certain embodiments, the structure has a modular design, combining a material configured for controlled release of therapeutic, diagnostic, and/or enhancement agents with a structural material necessary for gastric residence but configured for controlled and/or tunable degradation/dissolution to determine the time at which retention shape integrity is lost and the structure passes out of the gastric cavity. For example, in certain embodiments, the residence structure comprises a first elastic component, a second component configured to release an active substance, and, optionally, a linker. In some such embodiments, the linker may be configured to degrade.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139
THE BRIGHAM AND WOMEN'S HOSPITAL INC75 FRANCIS STREET BOSTON MA 02115

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bellinger, Andrew Wellesley, US 32 539
DiCiccio, Angela San Francisco, US 20 374
Eckhoff, Philip A Kirkland, US 143 1489
Glettig, Dean Liang Cambridge, US 19 409
Grant, Tyler Arlington, US 32 460
Jafari, Mousa Waltham, US 19 338
Langer, Robert S Newton, US 635 37250
Mo, Stacy Darien, US 17 345
Traverso, Carlo Giovanni Newton, US 108 824
Wood,, Jr Lowell L Bellevue, US 2836 53047
Zhang, Shiyi Shanghai, CN 41 457

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