Methods and systems for detecting an analyte or classifying a sample
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United States of America Patent
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Jul 12, 2022
Grant Date -
Apr 2, 2020
app pub date -
Sep 25, 2019
filing date -
Apr 16, 2012
priority date (Note) -
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Abstract
The present invention relates to methods and systems for detecting one or more analytes in a sample and/or for classifying a sample. In particular, the present invention relates to methods and systems which can be used to detect the analytes in real time and which rely on flowing through a microfluidic device one or more types of sensor molecule each comprising a domain that binds one or more analytes, a chemiluminescent donor domain and an acceptor domain, wherein the separation and relative orientation of the chemiluminescent donor domain and the acceptor domain, in the presence and/or the absence of analyte, is within ±50% of the Forster distance.
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