Treatment of kidney diseases associated with elevated AVP

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11354990
APP PUB NO 20200234552A1
SERIAL NO

16841098

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Abstract

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Disclosed are methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, thereby treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS810 VERMONT AVENUE N W WASHINGTON DC 20420

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carlson, Noel G Salt Lake City, US 7 14
Kishore, Bellamkonda K Sandy, US 9 17
Zhang, Yue Salt Lake City, US 291 1641

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