Genetic engineering of non-human animals for the production of chimeric antibodies

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United States of America Patent

PATENT NO 11352444
APP PUB NO 20170188557A1
SERIAL NO

15463752

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Abstract

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The invention provides non-human cells and mammals having a genome encoding chimeric antibodies and methods of producing transgenic cells and mammals. Certain aspects of the invention include chimeric antibodies, humanized antibodies, pharmaceutical compositions and kits. Certain aspects of the invention also relate to diagnostic and treatment methods using the antibodies of the invention.

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Patent Owner(s)

Patent OwnerAddress
ABLEXIS LLC10581 ROSELLE STREET SUITE 115 SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Green, Larry San Francisco, US 54 1607
Shizuya, Hiroaki South Pasadena, US 31 848

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