Compositions and methods of enhancing 5-hydroxytryptophan bioavailability

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United States of America Patent

PATENT NO 11337963
APP PUB NO 20210346345A1
SERIAL NO

15733423

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Abstract

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Provided are methods of enhancing bioavailability of enterally administered 5-hydroxytryptophan (5-HTP) in a subject in need thereof, said method comprising enterally co-administering low-dose carbidopa with said 5-HTP, as well as pharmaceutical formulations useful for the same. In some embodiments, the 5-HTP and/or low-dose carbidopa are provided as slow-release formulation(s).

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Patent Owner(s)

  • DUKE UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Caron, Marc G Hillsborough, US 54 574
Jacobsen, Jacob P R Durham, US 2 6

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