Nanoparticle delivery system for diseases associated with major basement membrane components of blood vessels accessible from blood stream

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United States of America Patent

PATENT NO 11337931
APP PUB NO 20210069119A1
SERIAL NO

16950327

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Abstract

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A targeting nanoparticle composition and method of treatment for diseases associated with major basement membrane components of blood vessels accessible from blood stream is presented. The composition includes pegylated perfluorocarbon nanoparticles having a targeting ligand attached that targets the basement membrane components, specifically collagen IV. The targeted nanoparticles may contain at least one pharmaceutically active agent capable of treating a glomerular disease such as lupus nephritis.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF SOUTH FLORIDA3802 SPECTRUM BLVD SUITE 100 TAMPA FL 33612

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Ruisheng Tampa, US 5 13
Pan, Hua Tampa, US 49 91
Wei, Jin Tampa, US 12 15
Wickline, Samuel A Temple Terrace, US 60 1079
Zhang, Jie Tampa, US 1052 8750

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