Immuno-based botulinum toxin serotype A activity assays

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United States of America Patent

PATENT NO 11332518
APP PUB NO 20210340229A1
SERIAL NO

17376416

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Abstract

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The present specification discloses SNAP-25 compositions, methods of making α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing α-BoNT/A antibodies.

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Patent Owner(s)

Patent OwnerAddress
ALLERGAN INC25254 DUPONT DRIVE IRVINE CA 92612

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aoki, Kei Roger Coto De Caza, US 187 4077
Fernandez-Salas, Ester San Mateo, US 120 2055
Garay, Patton E Long Beach, US 24 185
Hodges, D Dianne Tustin, US 28 243
Wang, Joanne Irvine, US 56 624
Wong, Lina Irvine, US 5 0

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