Method of producing proteins in filamentous fungi with decreased CLR2 activity

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United States of America

PATENT NO 11299522
APP PUB NO 20200308235A1
SERIAL NO

15779595

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Abstract

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The present invention relates to a method of producing a recombinant polypeptide a filamentous fungus which is genetically modified to decrease or eliminate the activity of cellulase regulator 2 (CLR2) and to express said recombinant polypeptide. The method further relates to a filamentous fungus Myceliophthora thermophila, which is genetically modified to decrease or eliminate the activity of CLR2 and the use of this filamentous fungus in the production of a recombinant polypeptide.

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Patent Owner(s)

Patent OwnerAddress
BASF SEGERMANY'S RHINE RIVER IN LUDWIGSHAFEN LUDWIGSHAFEN RHINELAND-PALATINATE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boehmer, Nico Mannheim, DE 3 2
Haefner, Stefan Speyer, DE 54 222
Hartmann, Holger Mannheim, DE 14 40
Thywissen, Andreas Heidelberg, DE 2 1

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