Cell lines for screening odorant and aroma receptors

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11267852
APP PUB NO 20180298069A1
SERIAL NO

15580110

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Abstract

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Provided herein is a cell line with improved odorant receptor function comprising an activated endogenous RTP1 gene, which further expresses an RTP1 protein. Further provided herein is a method for specifically activating an endogenous RTP1 gene in a eukaryotic cell using a CRISPR/Cas9 derived technique. Also provided herein is a method for identifying compounds with desired effects such as perfume or aroma modulators in said cell line.

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Patent Owner(s)

Patent OwnerAddress
FIRMENICH SA1242 SATIGNY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jeong, Hyo-Young Woodside, US 16 37
Pfister, Patrick Brooklyn, US 18 132
Rogers, Matthew Briarcliff Manor, US 48 3208

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