Peptides and method for treatment of cardiac arrest

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11260105
APP PUB NO 20200297813A1
SERIAL NO

16895161

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Abstract

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Modified peptides based on C-terminal PDZ binding domains of PTEN and PHLPP, or PDK1 interacting fragment of PKN2 are described as are methods of using the modified peptides for blocking the activity of PTEN, PHLPP and PKN2 and treating sudden cardiac arrest. A method for guiding treatment of cardiac arrest based on sorbitol or taurine levels is also provided.

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Patent Owner(s)

Patent OwnerAddress
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS352 HENRY ADMINISTRATION BUILDING 506 SOUTH WRIGHT STREET URBANA IL 61801

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Li, Jing Chicago, US 1112 6098
Vanden, Hoek Terry Chicago, US 2 1
Zhu, Xiangdong Chicago, US 12 59

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