Anti-TGF-beta antibodies and their use

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United States of America Patent

PATENT NO 11242384
APP PUB NO 20200399358A1
SERIAL NO

16931198

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Abstract

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The invention provides an improved pan-TGF-β antibody for treatment of conditions that are mediated by TGF-β, including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.

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Patent Owner(s)

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SANOFI46 AVENUE DE LA GRANDE ARMÉE PARIS 75017

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brower, Kevin Holliston, US 13 22
Finn, Patrick Franklin, US 24 163
Gregory, Richard C Framingham, US 5 13
Koduri, Rao Shrewsbury, US 7 17
Liu, Feng San Diego, US 583 7601
Malkova, Natalia Needham, US 12 44
Mankoo, Parminder Foster City, US 4 13
Pollard, Jack R Acton, US 4 13
Qiu, Huawei Westborough, US 70 353
Shapiro, Gary Arlington, US 20 303
Theilhaber, Joachim Cambridge, US 7 52
Winter, Christopher Swampscott, US 12 66
Yu, Marcella Fremont, US 11 185

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