Method and reagent for detecting ovarian clear cell adenocarcinoma

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11193936
APP PUB NO 20190170754A1
SERIAL NO

16272089

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Abstract

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The present invention aims to provide a method for detecting, with high sensitivity and specificity, ovarian clear cell adenocarcinoma, which is highly malignant, among benign and malignant ovarian tumors having various tissue types, and a reagent that can be used for the method. The present invention provides NT-TFPI2, which is a novel processed tissue factor pathway inhibitor 2 polypeptide, as a new detection marker for ovarian clear cell adenocarcinoma. The detection of ovarian clear cell adenocarcinoma is carried out by measuring the amount of NT-TFPI2, or the total amount of NT-TFPI2 and intact TFPI2. The reagent for detecting ovarian clear cell adenocarcinoma contains an antibody that specifically recognizes NT-TFPI2 and intact TFPI2.

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Patent Owner(s)

Patent OwnerAddress
PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITYYOKOHAMA-SHI KANAGAWA 236-0027

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arakawa, Noriaki Yokohama, JP 12 205
Hirano, Hisashi Yokohama, JP 8 38
Miyagi, Etsuko Yokohama, JP 6 6
Ohtake, Norihisa Ayase, JP 11 1

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