HPPD variants and methods of use

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United States of America Patent

PATENT NO 11180770
SERIAL NO

16489620

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Abstract

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In the present invention, HPPD polypeptides and plants containing them showing a full tolerance against one or more HPPD inhibitor herbicides belonging to various chemical classes are described. A set of mutant HPPD polypeptides have been designed which have either no or only a significantly reduced affinity to HPPD inhibitor herbicides and, at the same time, the rate of dissociation of the HPPD inhibitors of the mutant HPPD polypeptide is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors. In particular, isolated polynucleotides encoding mutant HPPD polypeptides conferring tolerance to HPPD inhibitor herbicides belonging to various chemical classes are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.

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Patent Owner(s)

Patent OwnerAddress
BASF AGRICULTURAL SOLUTIONS SEED US LLCFLORHAM PARK NJ 07932

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balven-Ross, Heike Solingen, DE 3 4
Coco, Wayne Pulheim, DE 10 12
Dubald, Manuel Raleigh, US 16 53
Geske, Sandra Cologne, DE 5 16
Laber, Bernd Idstein, DE 31 199
Lange, Gudrun Kelkheim, DE 21 156
Linka, Marc Düsseldorf, DE 31 26
Pawlowski, Nikolaus Cologne, DE 8 17
Poree, Fabien Valbonne, FR 25 158
Strerath, Michael Düsseldorf, DE 16 102
Tebbe, Jan Cologne, DE 27 154
Thies, Christina Dormagen, DE 4 4
Weber, Ernst Langenfeld, DE 27 65
Wobst, Nina Cologne, DE 7 18

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