Method for the production of multiple-unsaturated fatty acids in transgenic organisms

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United States of America Patent

PATENT NO 11180769
APP PUB NO 20190323024A1
SERIAL NO

16509247

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Abstract

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The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with Δ5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode Δ6-desaturases, Δ5-desaturases, Δ4-desaturases and/or Δ6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained. The invention also relates to the nucleic acids, and constructs, vectors and transgenic organisms comprising the same, as well as oils, lipids and/or fatty acids produced by the process according to the invention and to their use.

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Patent Owner(s)

Patent OwnerAddress
BASF PLANT SCIENCE GMBH--- --- LUDWIGSHAFEN D-67056

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abbadi, Amine Ebergötzen, DE 12 332
Bauer, Jörg Limburgerhof, DE 62 962
Cirpus, Petra Mannheim, DE 42 821
Domergue, Frederic Hamburg, DE 11 319
Heinz, Ernst Hamburg, DE 30 945
Kirsch, Helene Hamburg, DE 2 0
Qiu, Xiao Saskatoon, CA 51 734
Schmidt, Astrid Hamburg, DE 8 1
Sperling, Petra Hamburg, DE 5 88
Vrinten, Patricia Saskatoon, CA 17 253
Zank, Thorsten Mannheim, DE 29 679

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