Compositions and methods relating to salts of specialized pro-resolving mediators
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United States of America Patent
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Oct 5, 2021
Grant Date -
Jun 11, 2020
app pub date -
Aug 8, 2019
filing date -
Jun 3, 2016
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Abstract
The present invention relates to compounds of Formulas I-IV and compositions comprising same, including pharmaceutical compositions. The compounds of Formulas I-IV represent new salt forms of specialized pro-resolving mediators (“SPMs”) which include lipoxins, resolvins, protectins, and their aspirin-triggered counterparts. The SPM salts described here contain at least one or two SPM molecules ionically bound to at least one basic function that is provided by a scaffold as described in Formulas I-IV. Also provided are methods for pharmaceutical and non-pharmaceutical uses of such compounds and compositions describing same.
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